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Redeeming India’s Nuclear Power Promise: A Clean Energy Imperative for 2047

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Introduction: A Nuclear Vision for Viksit Bharat@2047 As India marches toward its ambitious goal of becoming a developed nation by 2047, energy security stands as a pivotal pillar in the vision of Viksit Bharat . Amid the global climate crisis and rising energy demands, nuclear power has re-emerged as a compelling solution. India’s commitment to achieving 100 GW of nuclear power capacity by 2047 is both visionary and necessary—but achieving this requires a strategic shift in policy, participation, and international cooperation. While India’s nuclear energy sector has traditionally been a tightly controlled domain under government monopoly—primarily led by the Department of Atomic Energy (DAE) and Nuclear Power Corporation of India Limited (NPCIL) —it is now imperative to welcome private sector investments and foreign partnerships. A reformed nuclear ecosystem can unlock the full potential of atomic energy as a clean, reliable, and scalable contributor to India’s net-zero aspiration...

Selective Silencing: Impact on Genetic Expression and Disease Outcomes

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Selective Silencing: Understanding Its Role in Disease Outcomes and Genetic Expression

Researchers at Columbia University have revealed the fascinating concept of selective silencing and its potential impact on disease outcomes. This process involves the selective inactivation of one copy of a gene inherited from one parent, which can influence genetic expression and potentially affect disease susceptibility. Here's a detailed explanation:

1. Understanding Selective Silencing

  • Gene Copies in Cells: Every cell in the body (except sperm and eggs) contains two copies of each gene, inherited from both parents.
  • Selective Inactivation: In some cells, one of the copies of a gene is selectively silenced, meaning it is blocked from expressing its genetic message. This selective silencing can affect how genes function and influence an individual's overall health.

2. Significance of Selective Silencing

  • Blocking Gene Messages: Silencing refers to the process of preventing a gene from sending its message, essentially turning off one parent’s version of the gene.
  • Impact on Disease: This process could explain why some individuals who carry disease-linked genes do not show symptoms. The silencing of one parent’s gene copy might prevent the expression of a disease-causing mutation, keeping the individual symptom-free despite carrying the genetic predisposition.

3. Potential Implications for Health

  • Understanding selective silencing could lead to new insights into genetic diseases, their expression, and potential treatments. It may also provide clues as to why certain genetic diseases remain dormant or asymptomatic in some carriers.

Selective Silencing is an emerging concept with profound implications for genetics, disease management, and healthcare, offering a new avenue for understanding and treating genetic disorders.

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